A person's immune system plays an important function. It protects one from various ailments allowing one to function well in his lifetime. The immune system will ward off any agent that will be harmful to ones health. There are instances however where function is weakened and aliments invade the body. In such time you may rely on interventions that will be able to improve the defenses of your body. There are many measures which you could take that will improve your health. There are some cases though where immune function would have to suppressed, one way to do so is the use of liposomal clodronate.
A healthy immune system has the ability to determine the cells of your own body and those that are foreign. The defenses of the body will coexist with the cells that it recognizes as its own. When they encounter cells that are foreign to the body though it will launch an attack that will keep these cells from harming your body.
One example of foreign tissue are viruses that could cause different diseases. There are also treatments that the immune system may reject such as those in transplanted tissues. This is because the tissues that are of another person's carry markers which your immune system will not recognize as being your own.
There are also times when the body will attack its own. This is what happens with autoimmune diseases. The body's defenses will mistake its own tissues as a foreign cell and launch defenses on it. It could be caused by some other disease or medication that predisposes you to such or could be genetic.
An organism will be protected against infections through the layered defenses of the immune system. Physical barriers are present that will protect ones body from pathogens. If said barriers get breached, your body's innate immune response provides it with immediate response. The response it produces is nonspecific. If this will be insufficient, innate immune response triggers the action of adaptive immune system which provides a specific response for every pathogen. That response is then retained so that a faster and a stronger response is possible when the same pathogen is again encountered.
An important component of your immune system are macrophages. They are a type of white blood cells that functions in both innate and adaptive immunity. Their role will be engulfing pathogens and then digesting them.
Liposomes are lipid vesicles that are prepared artificially which consist of lipid bilayers. These are used in the administration of nutrients as well as of drugs. They can encapsulate molecules which are strongly hydrophilic such as clodronate. A free clodronate will not pass bilayers of the liposome easily so after delivery into cells, it would not be able to escape. After phospholipids are destroyed, substance gets released to the cell being targeted. Through apoptosis the cell will be destroyed.
This helps so that macrophages are effectively eliminated. Thus, there would no longer be cells attacking tissues that are introduced purposely. They also eliminate cells that attack your own body.
Such substance is useful in medicine. Steps are made so that people are given better options at treatment. One such option is liposomal clodronate.
A healthy immune system has the ability to determine the cells of your own body and those that are foreign. The defenses of the body will coexist with the cells that it recognizes as its own. When they encounter cells that are foreign to the body though it will launch an attack that will keep these cells from harming your body.
One example of foreign tissue are viruses that could cause different diseases. There are also treatments that the immune system may reject such as those in transplanted tissues. This is because the tissues that are of another person's carry markers which your immune system will not recognize as being your own.
There are also times when the body will attack its own. This is what happens with autoimmune diseases. The body's defenses will mistake its own tissues as a foreign cell and launch defenses on it. It could be caused by some other disease or medication that predisposes you to such or could be genetic.
An organism will be protected against infections through the layered defenses of the immune system. Physical barriers are present that will protect ones body from pathogens. If said barriers get breached, your body's innate immune response provides it with immediate response. The response it produces is nonspecific. If this will be insufficient, innate immune response triggers the action of adaptive immune system which provides a specific response for every pathogen. That response is then retained so that a faster and a stronger response is possible when the same pathogen is again encountered.
An important component of your immune system are macrophages. They are a type of white blood cells that functions in both innate and adaptive immunity. Their role will be engulfing pathogens and then digesting them.
Liposomes are lipid vesicles that are prepared artificially which consist of lipid bilayers. These are used in the administration of nutrients as well as of drugs. They can encapsulate molecules which are strongly hydrophilic such as clodronate. A free clodronate will not pass bilayers of the liposome easily so after delivery into cells, it would not be able to escape. After phospholipids are destroyed, substance gets released to the cell being targeted. Through apoptosis the cell will be destroyed.
This helps so that macrophages are effectively eliminated. Thus, there would no longer be cells attacking tissues that are introduced purposely. They also eliminate cells that attack your own body.
Such substance is useful in medicine. Steps are made so that people are given better options at treatment. One such option is liposomal clodronate.
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